Last edited by Shak
Tuesday, May 19, 2020 | History

8 edition of Drug-like Properties: Concepts, Structure Design and Methods found in the catalog.

Drug-like Properties: Concepts, Structure Design and Methods

from ADME to Toxicity Optimization

by Edward Kerns

  • 127 Want to read
  • 36 Currently reading

Published by Academic Press .
Written in English

    Subjects:
  • Life Sciences - Biochemistry,
  • Pharmacology,
  • Pharmacy,
  • Science,
  • Medical / Pharmacology,
  • Medical,
  • Medical / Nursing

  • The Physical Object
    FormatHardcover
    Number of Pages552
    ID Numbers
    Open LibraryOL10071883M
    ISBN 100123695201
    ISBN 109780123695208

    Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization PDF I have spent some of the last two days reading this book and I am very impressed with it. It is destined to become an authoritative text on the whole topic area of . Statistics-Based In Silico Methods for Toxicity In these programs, parameters are calculated for structures and substructure connectivity. Computational models are derived using QSAR and neural net techniques. Topkat uses a QSAR-based model. Structures are evaluated using electrotopological structural descriptors and fit withFile Size: KB.

    Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates. This valuable resource explores physiochemical properties, including solubility and permeability, before. Find many great new & used options and get the best deals for Drug-Like Properties: Concepts, Structure Design and Methods - From ADME to Toxicity Optimization by Edward H. Kerns and Li Di (Trade Cloth) at the best online prices at eBay! Free shipping for many products!

    Read "Drug-like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization" by Li Di available from Rakuten Kobo. Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, Brand: Elsevier Science. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Enter your mobile number or email address below and we'll send you a link to download the free Kindle App. Then you can start reading Kindle books on your smartphone, tablet, or computer - no Kindle device : Li Di, Edward H Kerns.


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Drug-like Properties: Concepts, Structure Design and Methods by Edward Kerns Download PDF EPUB FB2

Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance.

This book aims at explaining all basic concepts of what are drug-like properties. This is a relatively comprehensive manuscript including a detailed description of the experiment corresponding to the explained concepts.

I recommend this book to all medicinal chemist willing to Cited by: Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, Cited by: Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, 5/5(1).

This book aims at explaining all basic concepts of what are drug-like properties. This is a relatively comprehensive manuscript including a detailed description of the experiment corresponding to the explained concepts.

I recommend this book to all medicinal chemist willing /5(9). Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed. Book Review of Drug-like Properties: Concepts, Structure Design, and Methods.

Purchase Drug-like Properties: Concepts, Structure Design and Methods - 1st Edition. Print Book. ISBN Book Edition: 1. Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization Edward Kerns, Li Di Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product.

Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of.

Goodreads helps you keep track of books you want to read. Start by marking “Drug-Like Properties: Concepts, Structure Design and Methods: From Adme to Toxicity Optimization” as Want to Read: Want to Read saving 4/5(15). The NOOK Book (eBook) of the Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization by Li Di, Edward H Kerns | Due to COVID, orders may be delayed.

Thank you for your : Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization by Li Di. Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to.

Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

This valuable resource explores physiochemical properties, including solubility and permeability, before exploring how compounds are absorbed, distributed, Author: Li Di, Edward H Kerns. Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

This valuable resource explores physiochemical properties, including solubility and permeability, before Brand: Elsevier Science. Buy Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization 1 by Kerns (ISBN: ) from Amazon's Book Store.

Everyday low prices and free delivery on eligible orders/5(8). Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization Currently unavailable.

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product.5/5(6).

Drug-Like Properties - Concepts, Structure, Design, and Methods from ADME to Toxicity Optimization (2nd Edition) Details This book provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

Drug-Like Properties: Concepts, Structure Design and Methods from ADME to Toxicity Optimization, Second Edition, provides scientists and students the background and tools to understand, discover, and develop optimal clinical candidates.

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I could comprehended almost everything using this written e ebook. I File Size: 59KB.Concepts, Structure Design and Methods from ADME to Toxicity Optimization. Author: Li Di,Edward H Kerns; Publisher: Academic Press ISBN: Category: Science Page: View: DOWNLOAD NOW» Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, only a fraction have sufficient ADME (absorption, distribution.Find helpful customer reviews and review ratings for Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization at Read honest and unbiased product reviews from our users/5.